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The MHRA has authorised weight loss injections for specific indications, and prescribers must assess individual suitability based on comprehensive medical history, current medications, and overall health status
In cross-sectional studies, low circulating IGF-I levels were found to be associated with angiographically documented coronary artery disease[275] and may predict fatal ischemic heart disease[272], a significantly increased risk of ischemic stroke and congestive heart failure in elderly patients[276, 277], as well as a worse prognosis of recovery after an acute myocardial infarction[278]
Improves insulin sensitivity: A 2025 meta-analysis of 17 randomized controlled trials involving nearly 6,000 women found that HRT significantly reduced insulin resistance (HOMA-IR) in healthy postmenopausal women [8]
Talk to Your Doctor Use this GLP-1 diet plan for general food structure, small meal ideas, grocery planning, protein-first rhythm, and low-appetite support