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Extended Data Figure 3 Statistics of buried and exposed surface areas of 86 crystallized GPCR ligands
Osteogenesis During osteogenic differentiation native GLP-1 100 nM increased alkaline phosphatase (ALP) activity, mRNA expression and calcium deposition in human adipose derived stem cells (hASC) [22]
Combination therapy with PI3K and MEK inhibitors inhibited histone Kla (H3K18la) in TAMs and controlled tumor growth in 80% of PTEN/p53-deficient prostate cancer mice
therefore, theres no relevance whatsoever
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