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Research published in Free Radical Biology & Medicine found plasma malondialdehyde (a lipid peroxidation marker) increased 28% in subjects losing more than 1% body weight weekly, indicating oxidative damage outpacing antioxidant defenses
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Semaglutide(Ozempic, Rybelsus, Wegovy) from Novo Nordisk and Tirzepatide(Mounjaro, Zepbound) from Eli Lilly are the most famous GLP-1 drugs
The encouraging part is that new trials are unlocking more uses every year, and some clinics including ours are already helping patients with chronic pain and autoimmune disease access these medications, including in microdoses, even when they dont fit the traditional weight-loss criteria
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