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Food intake, particularly carbohydrates and fats, suppresses ghrelin-mediated GH release by up to 80% (Nass et al., J Clin Endocrinol Metab, 2008)
More specifically, it seems to be a combination of: documenting the medical needs of patients (probably through intake forms) who are experiencing or have experienced nausea, vomiting, or other drug tolerance-related issues associated with GLP-1s (which are discussed in this Hims paper), and providing personalized compounded semaglutide in doses outside the 10% threshold to address those documented medical needs
FEBS Lett (1995) 358(3):21924
