Ultimately, GLP-1based adjunct therapy in type 1 diabetes should be viewed as a personalized option rather than a standard treatment

Specific scenarios where Mounjaro might be considered include: Insufficient weight loss : Patients who have not achieved expected weight loss by 1218 months post-operatively despite adherence to dietary and lifestyle recommendations (some services use thresholds such as 50% excess weight loss, though criteria vary) Weight regain : Individuals experiencing significant weight regain after initial successful weight loss Persistent type 2 diabetes : Patients whose diabetes has not achieved remission or adequate control following surgery, particularly if weight loss has been suboptimal Weight loss plateau : Those who have reached a plateau well above their target weight despite continued adherence to behavioural modifications Before considering Mounjaro, your bariatric team will typically conduct a comprehensive reassessment including evaluation of dietary adherence, physical activity levels, psychological factors affecting eating behaviours, and potential surgical complications such as gastric sleeve dilation
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Comprehensive assessment for DSPN involves evaluating small and large fiber function through temperature/pinprick sensation and 128-Hz tuning fork vibration sensation, respectively, along with 10-g monofilament testing to identify feet at risk of ulceration and amputation [46]