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The glucagon component appears to turn up energy expenditure, which is the mechanistic reason its weight-loss numbers ran higher than single and dual agonists in clinical testing

Right now, the only options on the market are semaglutide and tirzepatide, Papamargaritis says

You want to manage or avoid potential side effects

Whilst primarily prescribed for diabetes management, emerging research suggests Ozempic may also reduce systemic inflammationa key factor in cardiovascular disease and metabolic disorders

It reduces appetite and helps people eat less, which explains why studies show larger weight loss results over time