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Here, structural similarity between viral antigens and beta-cell autoantigens can lead to cross-immune responses

Glycodelin mediates the increase in vascular endothelial growth factor in response to oxidative stress in the endometrium

Certain populations face higher deficiency risk: vegetarians and vegans (B12 is primarily found in animal products), adults over 50 (decreased stomach acid reduces B12 absorption), individuals with digestive disorders like Crohn's disease or celiac disease, and those taking medications like metformin or proton pump inhibitors

Concurrently, L-lactate induces HIF-1 and ROS accumulation, disrupts the G2/M checkpoint, and impairs DDR mechanisms