Small observational studies have reported modest weight loss, but these typically lack adequate controls for dietary modification, exercise, and placebo effects
This can make it easier to burn fat and maintain a healthy weight
Fluorescence polarisation assays quantify binding interactions with dissociation constants in the low micromolar range, establishing specific actin-binding domain engagement
Inhibiting NNMT increases NAD+ levels in fat cells, Justin Kitchens, FNP-C Functional Medicine Practitioner Board-certified Family Nurse Practitioner specializing in peptide therapy, hormone optimization, medical weight loss, and regenerative wellness
In research subjects, this results in measurable changes in feeding patterns, caloric intake, and appetite-related behaviors