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We found that cisplatin treatment caused a decrease in mitochondrial biogenesis (PGC-1, NRF-1, TFAM, mtDNA, ND1), mitochondrial mass (Porin and Citrate synthase activity) and fusion index (MFN2, Drp1), together with changes in the expression of autophagy-related genes (AKT/FoxO pathway, Atg1, Beclin1, LC3AII, p62) and enhanced ROS production (PRX III, MnSOD)
In particular, a positive association between members of the genus Dorea , Bifidobacterium and R
A prescription refill notification system was started to remind clinicians to reach out to patients 1 week before their medication ran out
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