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doi: 10.1002/pros.21158 142 RiedemannJMacaulayVM
People with diabetes, particularly severe diabetes, tend to lose less weight with GLP-1s than people without diabetes, so microdosing is less likely to be as effective, though their dose should only be increased as they tolerate it. George said that in her professional opinion, microdosing is a potential option for patients with smaller amounts of weight to lose or as a bridge to start, or wean off, regular GLP-1 medications
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For some patients, smaller divided doses may reduce nausea and digestive side effects by creating less abrupt medication peaks
Ihenetu K, Molleman A, Parsons ME, Whelan CJ
