Both medications have shown positive results for weight loss, but choosing the right one depends on different factors, such as health conditions, lifestyle, and long-term goals
Beyond weight loss, GLP-1 medications improve insulin signaling, reduce systemic and neuroinflammation, enhance mitochondrial efficiency, and exert direct effects on neurons and glial cells to maintain neurological cell health [2]
Dosages Vary Widely: Peptide dosages are highly specific to the peptide, research goal, and subject, typically ranging from micrograms to milligrams daily or weekly
Sulphonylureas (e.g., gliclazide, glimepiride): These medications stimulate insulin release and carry an inherent hypoglycaemia risk
Retatrutide may be worth waiting for only in rare cases: patients who've maximized results on both approved options