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Tirzepatide works by targeting multiple pathways involved in hunger regulation and metabolism
Eight in month two
And the published study, while valuable, was retrospective, company-authored, and lacks a control group - limitations that any informed consumer should weigh alongside the results
The SURMOUNT-1 trial showed 22.5% average weight loss with tirzepatide at 15 mg, compared to 14.9% with semaglutide at 2.4 mg in the STEP-1 trial
The company said it halted the research after discovering that the most promising agent posed a cardiovascular risk for individuals with a particular genetic defect. The company did not disclose the name of the agent
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