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I posted a poll on Twitter that asked learners/users you would replace vitamin B 12 in a patient with pernicious anemia, focusing on the choice between intramuscular (IM) and oral (PO) routes

These shots keep Vitamin B12 levels good and stop deficiency from coming back

Current Pharmaceutical Design, 26(25), 28732883

For patients seeking weight loss who request B12 injections, GPs should: Assess for genuine deficiency through appropriate blood tests rather than empirical treatment Provide education about the lack of evidence supporting B12 for weight loss in non-deficient individuals Explore underlying concerns about weight and energy levels, addressing these through appropriate channels Signpost to evidence-based resources such as NHS weight management services according to local pathways Patients should contact their GP if they experience unexplained fatigue, neurological symptoms (numbness, tingling, balance problems), or signs of anaemia (pallor, breathlessness, palpitations), as these may indicate B12 deficiency requiring investigation

For someone starting at 220 pounds, that translates to roughly 46 pounds of total weight reduction over a standard treatment course