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Elhelaly, A
Proteostasis decline may also contribute to oocyte aging through impaired protein folding, aggregation, and reduced activity of the ubiquitinproteasome and autophagy systems
The hyper-concentrated mix in Scenario 3 might be suitable for protocols requiring very large doses, but it introduces a higher margin for error with smaller dose measurements
Future clinical trials could explore alternative methods, such as intra-articular injections
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