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In streptozotocin-induced diabetic mice, Ex-4 has been observed to regulate the cell cycle via the PKA/activating transcription factor 1 (ATF-1)/-catenin/cyclin D1 pathway, thereby enhancing proliferation of -cell [34]

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GLP-1 receptor agonist , it mimics glucagon-like peptide-1 (GLP-1), a natural digestive hormone that plays a crucial role in regulating appetite and blood sugar levels