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SaccoRLKasnerSEBroderickJPCaplanLRConnorsJJCulebrasAet al
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One study suggests that the decrease in vagal signaling seen with HFD feeding is due to upregulation of K+ channels in the nodose ganglia, increasing hyperpolarization of VANs 67 , while other studies have implicated changes in the gut microbiota as a contributor to vagal afferent desensitization during HFD feeding (see the Gut microbiotabrain connection section)
Sorensen, G
Hrubys published work is relevant to this article because it connects peptide chemistry, alpha-MSH analog design, and melanocortin receptor selectivity
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