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At first, doctors prescribed these drugs to people with type 2 diabetes because these medications were designed to help the pancreas produce insulin. 1 But in the past few years, doctors have begun prescribing them for weight loss after the Food and Drug Administration approved GLP-1s for people with obesity

Tang QQ, Gronborg M, Huang H, et al

Sample preparation and liquid chromatography-mass spectrometry analysis A 100-L aliquot of plasma was mixed with 400 L of ice-cold chloroform-methanol (2:1, v/v) containing stable isotope-labeled internal standard L-carnitine-d3

Do Not Use Berberine If Pregnant or breastfeeding: authoritative guidance warns against use, and it should not be given to infants due to newborn jaundice/kernicterus risk

Certain antibiotics, particularly those that may affect gastrointestinal function, require careful monitoring when used concurrently with this combination therapy