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Prescription rate of GLP-1s based on diagnosis Source: Piaopiao, L et al JAMA Network Open October 31, 2025 Research published in JAMA Network Open evaluated trends in prescribing of GLP-1 agents from 2010 through the end of 2024 using the Cosmos data warehouse, which has at least some medical records for 300 million Americans
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In most cases, however, the modest heart rate increase associated with GLP-1 receptor agonists can be managed effectively in the primary care or endocrinology setting with appropriate monitoring and patient education
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