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Haematologica 103 , 770777 (2018)
The conjugates formed during Phase II metabolism are often less lipophilic than the parent compounds or Phase I metabolites, making them more soluble in water and easier to eliminate through urine or bile
As a key molecule in regulating cell pyroptotic necrosis, the absence of GSDMD reduces the degree of myocardial fibrosis after myocardial infarction, and decreases IL-1 released by infiltrating myeloid cells in the heart, thus playing a cardioprotective role (109)
(2024, December 12)
Reichenbach, H
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