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Another member of the natriuretic peptide family, A-type natriuretic peptide (ANP), which also has diuresis activity, was shown to be stimulated by exenatide, a GLP-1 receptor agonist (108)

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GIP receptor activation enhances insulin secretion and is hypothesized to affect fat metabolism, while GLP-1 receptor agonism promotes satiety, slows gastric emptying, and reduces appetite

Kessler suggests that medications like Ozempic promise long-term weight-loss benefits, but they may not address the underlying metabolic disorder that may be driving the persons excess weight

Subcutaneous injection typically produces only mild surface-level pressure