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To our knowledge, however, there are currently no reports describing how GLP-1 receptor agonist treatment modulates the expression of BDNF, leptin, ghrelin, NPY, -MSH, or AgRP in the context of MC4R deficiency

In contrast, the metabolic profile PNA mice was unaffected after intervention with lower doses of the dual- and triple-agonists, as well as with metformin (Fig

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However, their impact on cardiac structure and function in HF with preserved ejection fraction (HFpEF) and reduced ejection fraction (HFrEF) remains unclear

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