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Chronic stress and poor sleep elevate cortisol chronically, which can partially counteract the appetite-suppressing effects of GLP-1 therapy

Because the 2nd and 3rd hits are modifiable, the new model predicts that if CDR-activating air and water pollutants are decreased, new prenatal and newborn screening methods are used to identify the most vulnerable children, co-occurring medical conditions are treated, and new supports for metabolic and neuroimmune resilience are given to those children at increased risk, that like phenylketonuria (PKU) 12 , the most disabling symptoms of ASD can be prevented before they occur in some children, and decreased in others

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