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At the same time, inhibiting NNMT also helps preserve another important molecule: S-Adenosyl Methionine (SAM)

In dietinduced obese mice, NNMTi treatment significantly reduced liver weight, liver volume, and hepatic triglyceride levels, alleviated hepatic steatosis and inflammatory infiltration, downregulated inflammatory factors (such as TNF and IL6) and lipogenic genes (such as FAS), and upregulated lipolytic genes (such as ATGL) in the liver

A single missed dose has minimal impact on overall results

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