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Chang N, et al

Two commonly studied reference compounds in this space are CJC-1295 with DAC and Ipamorelin as a standalone peptide, each representing a distinct mechanistic approach within GH pathway research

Ipamorelins clean selectivity isolates the direct GH-stimulating effects of GHS-R1a activation in the pituitary, while GHRP-2s additional hypothalamic GHRH-releasing and peripheral ghrelin-stimulating activities add dimensions to the research data that Ipamorelin alone cannot provide

After removing studies not meeting the inclusion criteria, we identified a total of four interventional studies that assessed the independent effect of exercise on histological outcomes in biopsy-proven NAFLD