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In this process, LCFA must be first activated into lipoyl-CoA via acyl-CoA synthetase (ACS) (30)

Transdermal patches offer continuous drug delivery, ensuring steady levels of the active ingredient in the bloodstream

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For children on valproate for epilepsy, which can lead to a deficiency of carnitine (see Interactions section), the doctor will likely prescribe a dose of 100 mg/kg of body weight per day, not to exceed 2,000 mg per day