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While these findings indicate intriguing research possibilities, ongoing exploration is required to clarify the full scope of these mechanisms
This includes gradually worsening blurred vision, increasing difficulty reading or recognizing faces, expanding blind spots, or persistent double vision
The rationale for adding it to tirzepatide is that calorie restriction and GI side effects from GLP-1 medications can reduce B12 absorption, potentially leading to deficiency over time
However, several safety considerations warrant attention
Overall prescribing rates (GLP-1 RA prescriptions per total prescriptions) in December 2025 increased slightly relative to September 2025 (+5.0%) and now account for more than 7% of all prescriptions
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