do you lose fat or muscle on semaglutide (GLP-1) Loss: Body Composition Changes and Findings How Semaglutide and Tirzepatide Affect

The appetite suppression from GLP-1 activation feels different from simple caloric restriction

According to recent studies published in the Journal of Clinical Investigation, semaglutide and similar drugs can reduce the rewarding effects of alcohol, cocaine, nicotine, and opioids in lab animals, and decrease the motivation to seek out these drugs and prevent relapse after withdrawal

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A decrease in NCOA4 levels increases iron levels in cells, leading to the Fenton reaction and thus reducing sensitivity to ferroptosis