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The combination of GLP-1 receptor agonists with amylin analogues or future ghrelin receptor-targeting therapies may provide greater reductions in body weight and adiposity than monotherapy

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Each 10-day course should be followed by a pause of at least four months

Advantage : Neither (tie) Summary and Verdict# CagriSema and tirzepatide achieve remarkably similar weight loss (20.4% vs 20.9%) through fundamentally different dual mechanisms -- amylin/GLP-1 versus GIP/GLP-1