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Urine testing is one of the most widely used approaches because its inexpensive, straightforward, and reliable for spotting many commonly misused substances, but it has its limitations
J Clin Invest 128:35583567 Miller TM, Cudkowicz ME, Genge A et al (2022) Trial of antisense oligonucleotide Tofersen for SOD1 ALS
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freezing causes ice crystal formation that ruptures peptide bonds irreversibly
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