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This review highlights the role of IGF-1 in skeletal muscle, its importance during myogenesis, and its involvement in different disease conditions. Finally, IGF-1 LR3 helps inhibit muscle breakdown, thus preserving muscle protein content and mass as shown in a study using a rat model of hind limb suspension (HLS)

Cells were blocked with 5% BSA in PBS and incubated with primary antibodies overnight

it helps protect the cellular DNA from UV-induced damage

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