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In vitro cardiac myocyte assays and isolated perfused heart models (Langendorff preparations) show that hexarelin can attenuate ischemia-reperfusion injury, reduce apoptosis in cardiomyocyte cultures, and improve post-ischemic hemodynamic recovery independent of GH elevation

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The combined effect exceeds the sum of individual effects

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Astroglia as a cellular target for neuroprotection and treatment of neuro-psychiatric disorders