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This eventually prevents mitochondrial damage and the cytosolic release of oxidized mtDNA, a direct activator of NLRP3, limiting the processing of mature IL-1 69

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7 Conclusion and future directions Future research should focus on translating preclinical findings to human applications, particularly through chronobiological studies of hormonal-taste interactions and advanced computational modeling of individual taste-metabolism relationships

Results vary by skin type, dosage consistency, and individual response