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Think of it like a project manager for your body's internal construction crew
It gives you clean, round numbers for standard doses easy to measure, hard to mess up
Actual out-of-pocket cost will depend on insurance coverage, manufacturer savings programs, and the competitive landscape at the time of launch
Notably, cell death of erythrocytes cannot be triggered by staurosporine [23], which is a potent apoptosis-inducing agent, but it is triggered by the Ca 2+ ionophore ionomycin [79]
It is also widely recognized that GBCAs are relatively toxic, and the large size of the GBCA molecule limits its extravasation when BBB permeability is low (Montagne et al., 2016a,b
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