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Collectively, the functional states of macrophages extend beyond the simplistic M1/M2 framework, forming a multidimensional continuum shaped by signaling networks, epigenetic regulation, and metabolic reprogramming, which profoundly influences their diversity and adaptability in both physiological and pathological contexts

Best for Injury Recovery and Systemic Healing: Injectable Injectable BPC157 is the most effective form for: Muscle, tendon, and ligament repair Joint pain and inflammation Post-surgical healing and performance recovery This is the most studied form, featured in nearly all preclinical trials and veterinary applications

10.1007/s00401-016-1660-z Acta Neuropathol