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Across both drugs, persistence rates among patients on GLP-1 therapy for obesity is meaningfully lower relative to the type II diabetes cohort
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Long before microaneurysms, dot-blot hemorrhages, or hard exudates become visible on fundus photographs or ophthalmoscopy, the retina has already sustained measurable neuronal and synaptic loss, reactive gliosis, impaired neurovascular coupling, and subtle but objective deficits in contrast sensitivity, color discrimination, dark adaptation, and electrophysiological responses
A change in coverage could put pressure on other insurance companies to expand access
Although there are some inter-class differences, robust randomized controlled trials have demonstrated that use of some of these drugs can improve clinical outcome in individuals with T2D
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