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PubMed Central , Environmental Health Perspectives , vol

Endoscopic Image of Melanosis Coli

Some promising approaches include the following: - Garlic-derived allicin: reduces TMAO in murine models (C57BL/6 mice), suggesting anti-atherosclerotic potential ( - TMA lyase inhibitors: synthetic compounds (e.g., fluoromethylcholine, FMC) that irreversibly inhibit CutC/D ( - Probiotics: specific strains can lower TMAO levels (Vasquez et al., 2019

It is reported that treatment of CRC cells with luteolin, a naturally occurring flavonoid which is an agonist of PPAR, increased mRNA and protein expression of OCTN2 in a time- and dose-dependent manner, enhancing the intracellular accumulation of oxaliplatin (Qu et al., 2014)