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Moving from Tirzepatide to Semaglutide If you are switching from tirzepatide to semaglutide, your healthcare provider will likely have you start at a lower dose of semaglutide, usually 0.25 mg or 0.5 mg weekly

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The aim is to achieve a calorie deficit by eating 300 to 500 fewer calories than usual and increasing your exercise levels to induce and maintain weight loss, even after Wegovy treatment has ended