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A recently completed, first-in-human phase I/II study of A166 in 49 patients with relapsed/refractory cancers expressing HER2 antigen or amplified HER2 gene, including mCRPC, indicated safety and clinical efficacy 172

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doi: 10.1001/jama.2010.1014 122 HuangYLiRYeSLinSYinGXieQ

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February 20, 2020 Sirtuins and NAD+: The Secret Sauce for Extending the Human Lifespan David Sinclair, Ph.D

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