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To address these limitations, two new electronic PRO (ePRO) measures have been developed based on extensive involvement of women suffering from endometriosis in close accordance with the FDA PRO Guidance [21] and best practices established by the International Society for Pharmacoeconomics and Outcomes Research (ISPOR) PRO Good Research Practices Task Force [25, 26]
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Findings from research models do not establish safety or efficacy in humans
Any inflammation of the digestive system will affect many of these factors
They are used for different reasons
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