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54 In 40 subjects, aged 5184 years, 90 mg of a different bioavailable form of curcumin twice daily for 18 months improved performance on tests of memory and attention relative to placebo, and was also found to reduce accumulation of abnormal amyloid and tau (proteins implicated in Alzheimer disease) in the brain
Another study of three PWS patients on GLP-1 agonists showed sustained improvements in eating behavior and weight stabilization over 12 months, with no serious adverse events
The theoretical advantage of combining them lies in targeting multiple weight-loss mechanisms simultaneously
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