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GLP-1 medicines commonly cause stomach-related side effects such as nausea, vomiting, diarrhoea, and constipation, especially at the start of treatment and during dose escalation
Additionally, GLP-1 slows gastric emptying, which prolongs the sensation of fullness and further helps control portion sizes and calorie intake
Zhang Q., Yan L., Lu J., Zhou X
This means it has some potential for abuse or addiction, especially if not used properly
CT-388 would be the only branded dual GLP-1R/GIPR agonist with full exclusivity after tirzepatide faces generic competition in the 2036 to 2041 window
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