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10.1016/j.ejps.2021.105743 168 MohantyC.DasM.SahooS
Efficacy and Safety of Once-Weekly Semaglutide Monotherapy Versus Placebo in Patients with Type 2 Diabetes (SUSTAIN 1): A Double-Blind, Randomised, Placebo-Controlled, Parallel-Group, Multinational, Multicentre Phase 3a Trial
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Patients with higher baseline A1C values (above 9% or 10%) typically experience larger absolute decreases, though they may require higher tirzepatide doses or longer treatment duration to reach target levels
This successful clinical validation also lays the foundation for future research and development in natural metabolic health interventions
