A major review, or meta-analysis, of 12 depression/ALC trials that looked at data generated by almost 800 patients, found that supplementation scored improvements in symptoms that were comparable to what we see with the standard SSRI anti-depression pharma drugs
To support your liver function, and thus promote Detoxification Circuit health, you could consider the use of certain herbs such as dandelion, glutathione, and milk thistle
doi:10.1016/S0196-9781(99)00048-0
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In comparison to previous systematic reviews and meta-analyses, we were able to perform subgroup analyses based on the duration of treatment with GLP-1RAs