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The UK Clinical Pharmacy Association (UKCPA) Handbook of Perioperative Medicines notes that decisions should be based on individual patient factors and local protocols
There is no established evidence that semaglutide triggers new-onset IBD or worsens existing disease, but the absence of evidence should not be interpreted as evidence of safety in this specific population
If I am dealing with a patient who has had a history of NAION, that is probably the one situation I would tell the endocrinologist or internal medicine doctor to pause and have a real detailed discussion with this patient
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