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The background glucose-lowering therapy, referring to the common treatment received by all trial groups post-randomisation, varied across the trials
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Studies have shown that natural products such as polyphenols, terpenes, anthraquinones, and sulforaphane can activate the hepatocyte antioxidant defense system with Nrf2 as the core player, reduce oxidative stress damage, and protect the liver
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doi: 10.1056/NEJMoa1509225 78 MarsoSPDanielsGHBrown-FrandsenKKristensenPMannJFENauckMAet al
Proto et al
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