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GLP-1 alleviates NLRP3 inflammasome-dependent inflammation in perivascular adipose tissue by inhibiting the NF-B signalling pathway

Study reported that early-life inflammatory stressors can increase gut permeability via downregulating E-cadherin expression (an epithelial junction protein), mediated by elevated expression of MicroRNA-155 (37)

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Diverticulosis, Cleveland Clinic (2023) Ferrous sulfate supplementation causes significant gastrointestinal side-effects in adults: A systematic review and meta-analysis, Public Library of Science (2015) Diverticular disease, Johns Hopkins Medicine (Accessed 2026) Gut microbiota links vitamin C supplementation to enhanced mental vitality in healthy young adults with suboptimal vitamin C status: A randomized, double-blind, placebo-controlled trial, ScienceDirect (2024) Vitamin C, National Institutes of Health (2025) Update on the management of sigmoid diverticulitis, World Journal of Gastroenterology (2021) Magnesium glycinate: Is this supplement helpful for you?, Mayo Clinic (2024) Higher serum levels of vitamin D are associated with a reduced risk of diverticulitis, Clinical Gastroenterology and Hepatology (2013) Fibers and polyphenols in diverticular disease: from pathophysiology to management, Neurogastroenterology & Motility (2025) Dietary vitamin B6 intake modulates colonic inflammation in the IL10/ model of inflammatory bowel disease, ScienceDirect (2013) Foods for diverticulosis and diverticulitis, Johns Hopkins Medicine Probiotics in the treatment of diverticular disease