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Seek medical advice if you experience severe or worsening abdominal pain, persistent vomiting, signs of dehydration, blood in vomit or stools, severe constipation, or symptoms suggesting pancreatitis (severe upper abdominal pain radiating to the back)

Recent preclinical studies have demonstrated the potential of CRISPR-Cas9 genome editing to address key mutations underlying HCM, such as missense mutations in the MYH7 gene 318,319 and premature stop codon mutations in the MYBPC3 gene

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We report a significant reduction in total cholesterol in individuals with type 1 diabetes treated with a GLP-1 RA