A small study of healthy women taking 250 mg/day saw trends toward better elasticity and some wrinkle reduction (PMC Clinical Trial)
Sirt1-mediated deacetylation of PGC-1 alleviated hepatic steatosis in type 2 diabetes mellitus via improving mitochondrial fatty acid oxidation
The cyanide (prussic acid) in cyanocobalamin in supplements is generally not dangerous for the consumer
However, supplementation should always be part of a broader, comprehensive management strategy that includes aggressive pacing, nervous system regulation, and targeted medical care

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