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They found three miRNAs, miR-470, -669b, and -681, were upregulated in these mice and these three miRNAs directly bound to IGF-1R 3UTR, downregulated IGF-1R at both mRNA and protein levels, and led to reduced phosphorylation of both AKT and FOXO3a
CrossRef The active components of the Danshen-Shanzha herb-pair exert a protective effect on MASLD by synergistically promoting fatty acid oxidation via the activation of PPAR, Plin-5 and Plin-2 Ying Yang, Yaxing Li, Zirong Zhou, Hui Li, Yihan Ma, Wenjie Bi, Mengjiao Li, Xiaoli Liu, Qiang Jia, Liwen Han, Songsong Wang Journal of Ethnopharmacology .2026
Hamadneh L, Bahader M, Abuarqoub R, AlWahsh M, Alhusban A, Hikmat S
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