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In the brain of a mouse, the over-expression of -catenin levels mimics the anti-depressant-like effects of lithium 86 , while the knockout of -catenin leads to a depression-like phenotype 87,88
The researchers found that the glutathione group exhibited a significantly suppressed elevation of blood lactate (2.9 0.6 mM compared to 3.4 1.1 mM in the placebo group)
It is also an important thiol buffer, maintaining sulfhydryl groups in their reduced form, an additional mechanism for cellular signaling
Neurite outgrowth in PC12 cells stimulated by acetyl-L-carnitine arginine amide Neurochem Res 1995
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